In Vitro Solutions
Rdcthera offers a platform of in vitro analytical services in support of radiopharmaceutical R&D. We are committed to providing comprehensive and high-quality contract research for the successful development and progress of your radiopharmaceutical projects from concept through clinical application.
In Vitro Assessment in Radiopharmaceutical Development
The development of radiopharmaceuticals involves complex processes, especially rigorous in vitro testing and validation. In vitro analysis is very key to this area of study since it provides important data on the safety, efficacy, and pharmacokinetics of radiopharmaceuticals. These analyses are central in setting parameters of interaction between radiopharmaceuticals and biological systems and would allow researchers to fine-tune formulations of radiopharmaceuticals for anticipated in vivo behavior.
Fig. 1. Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging. (Raaphorst RM, et al., 2017)
Our Radiopharmaceutical In Vitro Solutions
At Rdcthera, we can offer our clients an in-house, fully integrated suite for in vitro analysis according to their requirements in radiopharmaceutical development. We specialize in conducting various complex assays and models that ensure delivery of robust, reliable data.
Our in vitro models are at the cutting edge of radiopharmaceutical testing. In this respect, our all-rounded testing platform offers in vitro models to run precise and predictive analyses that shall drive successful radiopharmaceutical development.
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Co-Culture Cell Models
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3D Cell Culture Models
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Tumor Xenograft Model
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Blood-Brain Barrier Model
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Organ-on-a-Chip Models
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Inflammatory Disease Models
Cell-Based In Vitro Assays
We at Rdcthera provide an extensive range of in vitro analytical development services for radiopharmaceuticals. Our services are tailored to suit innovative techniques and methodologies that guarantee accuracy, reliability, and data integrity for complete analysis.
Advanced Analytical Platforms
Programmed into our in vitro analysis services are state-of-the-art analytical platforms that enable a very high degree of accuracy and reliability. In having our laboratories so well equipped, we can provide not only high-resolution imaging techniques and sophisticated spectroscopy but also precise methods for quantification to generate data sets of the highest stringency to which radiopharmaceutical development has to adhere.
Applications of Our In Vitro Services
Our in vitro analysis services have a wide field of applications that help support many stages of radiopharmaceutical development.
- Preclinical evaluation and optimization
- Safety and toxicity assessments
- Mechanistic studies
- Pharmacokinetic modeling
- Submissions to regulatory authorities
In case you need credible and comprehensive in vitro analysis services for radiopharmaceutical development, Rdcthera is the one to contact today. We stand ready to help you turn your research ideas and goals into reality and take the first steps toward developing unique radiopharmaceuticals. Allow us to be your trusted partners in drug development.
Reference
- Raaphorst RM, Savolainen H, Cantore M, et al. (2017). Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET Imaging. Pharmaceuticals (Basel). 10(3):76.7
For research use only. Not intended for any clinical use.
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