In Vitro Models for Radiopharmaceutical Analysis
Rdcthera is dedicated to furthering the field of radiopharmaceuticals with our unrivaled CRO expertise. Specialized in a wide realm of in vitro models, we put at your disposal rigorous and reliable platforms by which the behavior and efficacy of radiopharmaceuticals can be explored. This works to your advantage in efficiently developing your drugs.
Introduction to Radiopharmaceuticals and In Vitro Models
Radiopharmaceuticals are special compounds used for medical imaging and therapy that bear radioactive isotopes. In view of this complexity of behavior, accurate analysis is required. In vitro models hence became major tools in such connections, allowing a controlled environment to determine the pharmacokinetics of radiopharmaceuticals, their toxicity, and therapeutic effects.
Fig. 1. Various approaches used in 3D cell culturing. (Badr-Eldin SM, et al., 2022)
Our In Vitro Models and Services
At Rdcthera, we provide a full portfolio of in vitro models to help radiopharmaceutical research answer a wide range of requirements.
| In Vitro Models |
Details |
| 2D Cell Culture Models |
It is ideal for initial screening and mechanistic studies.
It involves various human and animal cell lines tailored to different radiopharmaceutical targets. |
| Co-Culture Systems |
The interactions between the different cell types can be mimicked.
Mainly, it would be essential in investigating the contribution of the microenvironment to radiopharmaceutical behavior. |
| 3D Cell Culture Models |
It provides a more physiologically relevant environment with considerations of spheroids, organoids, and scaffold-based cultures predicting in vivo responses. |
| Custom In Vitro Model Development |
Tailor-made models are available to address specific needs of research studies.
Collaborative development shall ensure that it aligns well with your project goals. |
Advanced Analysis Platform
Our cutting edge analysis platform comprises high-throughput screening, next generation imaging techniques, and state-of-the-art data analytics. We align best-in-class technologies to provide detailed understanding regarding radiopharmaceutical behavior under various conditions, including
- High-content imaging and analysis
- Real-time PCR and molecular assays
- Flow cytometry and cell sorting
- Metabolomics and proteomics
Data and Information
Our services allow customers to generate pertinent data and information related to radiopharmaceuticals on cells and tissues, which would be useful in guiding drug development, toxicity assessment, and efficacy estimation of new treatments.
- Pharmacokinetics and biodistribution profiles
- Toxicity and safety assessments
- Mechanistic insights into radiopharmaceutical action
- Efficacy data in disease-specific models
- Predictive markers for clinical success
Our Capabilities of In Vitro Cell Assays
Rdcthera provides a variety of additional in vitro cell assays for drug screening and efficacy validation.
- Anticancer Efficacy Assay
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- Cell Proliferation Assays
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- Cell Migration/Invasion Assays
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- 3D Spheroid Formation Assay
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- Cell Cycle Analysis Assay
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In case of interest in our services or if you may have some questions, please don't hesitate to contact us. We are always ready to support you in a friendly manner and assist your research projects on their way to development. Rdcthera is your expert partner for in vitro models in radiopharmaceutical analysis.
Reference
- Badr-Eldin SM, Aldawsari HM, Kotta S, et al. (2022). Three-Dimensional in vitro Cell Culture Models for Efficient Drug Discovery: Progress So Far and Future Prospects. Pharmaceuticals (Basel). 15(8):926.
For research use only. Not intended for any clinical use.
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