In Vivo Imaging Services for Radiopharmaceutical Research
Rdcthera is proud to offer state-of-the-art CRO services in radiopharmaceuticals. Our in vivo imaging services are tailored to the requirements of your radiopharmaceutical research and development: exact data retrieved, reliable, and moving your projects forward. Our technology and a very experienced team form truly impressive imaging solutions tailor-made to meet the specific requirements of radiopharmaceutical studies.
In Vivo Imaging Research
In vivo imaging has been a significantly important link between the development and evaluation of radiopharmaceuticals. It will help researchers get insight into efficacy and safety by visualizing and quantifying the biodistribution, pharmacokinetics, and target engagement of radiotracers in living organisms. Researchers can also track the in vivo behavior of radiopharmaceuticals using in vivo imaging studies, optimize their dosing regimens, and assess their therapeutic potential.
Fig.1. In vivo [18F]FDS PET imaging in control rats and acute renal failure (ARF) rats. (Werner RA, et al., 2019)
Our In Vivo Imaging Services
Rdcthera offers a comprehensive suite of in vivo imaging services to meet all radiopharmaceutical research requirements. We offer state-of-the-art imaging modalities, sophisticated data analysis, and expert consultation so that your research objectives are explicitly and correctly met.
Preclinical Small Animal PET and SPECT Scanning Services
We offer high-resolution PET and SPECT scanning in small animals as part of our preclinical imaging services. In a perfect way, these modalities provide exquisite images of radiopharmaceutical distribution and kinetics, allowing in-depth analysis of biological processes at all levels of triviality. Our PET and SPECT systems are fully upgraded with the latest technology, realizing high sensitivity and spatial resolution to guarantee accurate imaging results.
Customized Image Acquisition Protocols
The success of any imaging study is founded on properly planned and executed image acquisition protocols. At its end, Rdcthera designs protocols that meet the needs of your study, considering radiotracer type, energy levels, and time windows.
Dynamic and Static Imaging Services
Dynamic or static imaging can be offered to capture real-time processes or static snapshots of radiopharmaceutical distribution. This dynamic imaging will add kinetic studies, whereas static imaging will provide details on anatomy and functioning. The approach in dual performs ensures comprehensive data collection for thorough analysis.
Expert Image Data Analysis
Image data analysis is an important step in getting significant information from imaging research studies. Rdcthera offers end-to-end analysis services, which include
- Image calibration
- Regions (volumes) of interest identification
- Time-activity curves
- Semi-quantitative analysis
- Tracer kinetic modeling
Our Capabilities
Rdcthera boasts extensive capabilities in in vivo imaging, with a wide range of available radiotracers and imaging modalities.
| Radiotracers |
Imaging Modalities |
| 18F-Small Molecules |
11C-Small Molecules |
PET/CT |
| 89Zr-Peptides and Antibodies |
68Ga-PSMA |
MR |
| 124I-Peptides and Antibodies |
64Cu-DOTATATE |
SPET/CT |
| Custom Radiolabeling Services |
|
Optical (Bioluminescence) |
Applications of Our In Vivo Imaging Services
Our in vivo imaging services are put to the following uses in radiopharmaceutical research
- Pharmacokinetics and biodistribution studies
- Evaluation of tumor target and therapeutic efficacy
- Drug development and validation
- Investigation of the biological pathway and mechanism
To apply our expertise in in vivo imaging, partner with Rdcthera in your radiopharmaceutical research. Discuss your project with us today, and find out how our services can hasten your research and development.
Reference
- Werner RA, Chen X, Lapa C, et al. (2019). The next era of renal radionuclide imaging: novel PET radiotracers. Eur J Nucl Med Mol Imaging. 46(9):1773-1786.
For research use only. Not intended for any clinical use.
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