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Immunophenotyping by Flow Cytometry

Rdcthera delivers dedicated flow cytometry immunophenotyping services in radiopharmaceutical research. Tailored to meet the needs of pharmaceutical, biotech companies, or researchers, we work with our clients on immune cell dynamics, characterizing cellular populations, and gaining insights into the immune responses that radiopharmaceuticals elicit.

Understanding Immunophenotyping in Radiopharmaceutical Research

Immunophenotyping is relevant as it will give detailed information about types and characteristics of the immune cells present in a sample. Therefore, be intrinsic to the understanding of the complex interactions among radiopharmaceuticals and the immune system. That allows researchers to

  • Characterize Immune Responses - Identify and quantify immune cell populations to determine how radiopharmaceuticals modulate immune responses.
  • Immune cell profile changes to use immune monitoring as a tool to test safety and efficacy of radiopharmaceuticals.
  • Enhanced drug development - Facilitating the development of targeted therapies through the understanding of immune cell behavior against radiopharmaceuticals.

Immunologic process induced by radiopharmaceuticals.Fig.1. Schematic illustration of immunologic process induced by radiopharmaceuticals. (Sun Q, et al., 2023)

Our Immunophenotyping Services

Rdcthera offers an array of services in immunophenotyping that will give a detailed understanding of immune cell populations and their interactions with radiopharmaceuticals. These services are tailored to suit the needs of pharmaceuticals, biotechnology firms, and research institutions.

Comprehensive Cellular Analysis
Multi-Parametric Flow Cytometry A next-generation flow cytometry that enables the simultaneous assessment of a number of markers on single cells, therefore creating a deep profile regarding immune cell populations.
Phenotypic Characterization Accurately identify cell surface markers that characterize various subsets of immune cells, including T cells, B cells, NK cells, and monocytes.
Intracellular Cytokine Staining It is able to detect and quantify cytokine production within immune cells, which informs about the functional status of immune cells and modulation of immune responses by radiopharmaceuticals.
Tailored Assay Development
Panel Design and Optimization Partner with our experts in designing and optimizing panels toward answering your research questions, ensuring maximum precision and reliability of results.
Custom Antibody Conjugation Offer custom conjugation of antibodies to a library of fluorochromes for flexible and accurate assay development tailored to your exact needs.
Customized Data Analysis Get custom data analysis services done for actionable insight, coupled with detailed reports.
Advanced Technology and Methodologies
Spectral Flow Cytometry Using spectral flow cytometry, we provide complete analysis of complex samples with overlapping fluorescent moieties, thus helping clients increase accuracy in the identification of cell populations.
High-Throughput Screening We can screen large sample sets at high throughput to accelerate your research and development.
Single-Cell Analysis We can provide single-cell analysis to elucidate cellular heterogeneity, which is understood to help in the identification of rare cell populations that would be otherwise critical in understanding radiopharmaceutical effects.

Why Rdcthera?

  • Radiopharmaceutical Expertise: Draw from our expertise in radiopharmaceutical research and immunology to move your projects forward.
  • State of the Art Facilities: Make use of our most advanced laboratory facilities equipped with the latest flow cytometry technologies.
  • Collaborative Approach: We provide personalized service through a relationship built with you and tailor our services according to your specific requirements for the success of your research effort.

Elevate your radiopharmaceutical research with our immunophenotyping services. Contact Rdcthera today to discuss your project needs and request a quote. Our team is ready to assist you in unlocking the full potential of your research.

Reference

  1. Sun Q, Li J, Ding Z, Liu Z. (2023). Radiopharmaceuticals heat anti-tumor immunity. Theranostics. 13(2):767-786.
For research use only. Not intended for any clinical use.

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Rdcthera offers efficient, customized, and professional R&D services related to radionuclide drug conjugates.

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